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Antibiotic Resistance

Antibiotic Resistance

overview

Antimicrobial resistance happens when germs like bacteria and fungi develop the ability to defeat the drugs designed to kill them. That means the germs are not killed and continue to grow. Resistant infections can be difficult, and sometimes impossible, to treat.

Bacteria, not humans or animals, become antibiotic-resistant. These bacteria may infect humans and animals, and the infections they cause are harder to treat than those caused by non-resistant bacteria. Antibiotic resistance leads to higher medical costs, prolonged hospital stays, and increased mortality.

What Does It All Mean?
Impermeable cell membrane Limiting uptake of a drug
Antibiotics need to penetrate into the bacteria to become effective Bacterial cell membrane (wall) adapts to its environment, changing to become an impermeable barrier blocking antibiotics from entering and harming the bacteria
Antibiotic inactivationStopping the drug from working
Bacteria produces a protein called an enzyme that inactivates the antibiotic before it can harm the bacteria.There are two (2) ways that bacteria can actually inactivate a drug.  Inactivation can occur by either:

1. Actual degradation of the drug by a protein call an enzyme that is produced by the bacteria
2. Or transfer of a chemical group to the drug
Target alteration
There are multiple components in the bacterial cell that may be targets of antimicrobial agents; and there are just as many targets that may be modified by the bacteria to enable resistance to those drugs.
Efflux pump
A type of protein pump found in bacteria cells that is responsible for transporting molecules out of the cell. Efflux pumps can pump out drugs or other toxic compounds from the bacterial cell, which can reduce the effectiveness of antibiotics and make it more difficult to treat bacterial infections. Some bacteria have multiple eflux pumps, making it even harder to treat infections caused by antibiotic-resistant bacteria.
FAQS

Frequently Asked Questions

01

What is the process for scheduling a cleaning service with MoBi Klenz?

You can schedule a cleaning service with MoBi Klenz online or by calling our customer service team. We will work with you to find a convenient time and date for your cleaning.

02

How often should I have my residential bins cleaned?

We recommend having your residential bins cleaned every two to four weeks, depending on the level of use and the weather conditions in your area.

03

Is MoBi Klenz an eco-friendly company?

Yes, MoBi Klenz is committed to providing eco-friendly cleaning services. We use biodegradable and environmentally safe cleaning products, and our equipment is designed to conserve water and energy.

04

Do you offer discounts for recurring cleaning services?

Yes, we offer discounts for customers who sign up for recurring cleaning services. Contact us for more information about our pricing and discounts.

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